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Ben Horowitz discusses how AI is transforming venture capital by accelerating decision-making, forcing firms to evaluate investors at the point of investment, and creating opportunities across multiple verticals while reflecting unprecedented market demand.
A deep dive into venture capital with Alex Rampell, exploring investment strategies, the changing startup landscape, AI's impact on labor and technology, and the critical importance of finding high-agency founders who can materialize labor, capital, and customers.
Alex Rampell discusses Andreessen Horowitz's $15B fundraise, venture capital strategies, and the evolving landscape of technology investment, emphasizing the importance of finding high-agency founders who can materialize labor, capital, and customers.
Ben Horowitz discusses how Andreessen Horowitz has scaled venture capital by building a platform that provides real support for entrepreneurs, focusing on network, operating experience, and helping founders navigate complex challenges across multiple technology sectors.
Ben Horowitz discusses the evolution of Andreessen Horowitz, explaining how they built a venture capital firm focused on providing entrepreneurs with network, advice, and platform services by scaling strategically and hiring experienced founders and CEOs.
In 2026, as companies rush to get AI agents into production, Keycard aims to help enterprises manage agent fleets by solving critical identity, authentication, and authorization challenges in this new agentic computing landscape.
An AI roundtable with Steven Johnson and Grant Lee explores how AI tools like NotebookLM and Gamma can enhance creativity, productivity, and decision-making across various professional domains, challenging the prevalent skepticism about AI's impact on human thinking.
In this a16z podcast episode, Marc Andreessen shares his insights on AI's transformative potential, discussing the technology's rapid development, its impact across industries, the ongoing race between open and closed source models, and the complex geopolitical dynamics of AI innovation between the US and China.
Laura Roeder shares how her bootstrapped SaaS, Paperbell, outlasted a $10M venture-backed competitor by staying lean, focusing on marketing, and avoiding over-engineering while serving the coaching software market.
In this episode, Larsen Jensen, a former Olympic swimmer and Navy SEAL turned venture capitalist, discusses the power of embracing difficult challenges, the importance of mental toughness, and how founders and investors can develop resilience by choosing hard paths with a meaningful purpose.
In a wide-ranging conversation, Marc Andreessen argues that AI will dramatically amplify human potential, challenge fears of existential risk, and serve as a democratizing force that can help solve global challenges while empowering individuals across every domain of human activity.
A panel of AI investment experts discuss the massive capital influx into AI, highlighting the insatiable demand for compute infrastructure, applications, and the potential risks of unequal wealth creation and energy constraints.
Ben Horowitz discusses leadership, culture, and innovation through stories about the internet's development, wartime vs. peacetime CEOs, and the critical importance of individual actions in shaping the world, drawing insights from historical figures like Toussaint Louverture and highlighting the unique challenges in bio and healthcare innovation.
Marc Andreessen and Ben Horowitz discuss Andreessen's Techno-Optimist Manifesto, exploring how technological innovation can drive progress, overcome pessimism, and create opportunities for marginalized communities through free markets and technological advancement.
Martin Casado discusses the AI boom, comparing it to the 1990s tech wave, and explains why he believes we're still in the early stages of the cycle, with significant opportunities for innovation and value creation in areas like AI coding and infrastructure.
A16z consumer investors discuss the state of consumer AI in 2025, highlighting the dominance of a few products, the rise of multimodal models, and the potential for innovative startups in the AI space.
Scott Kupor, director of the U.S. Office of Personnel Management, discusses a new two-year program called US TechForce aimed at recruiting 1,000 tech workers to help modernize government infrastructure and address early career pipeline challenges in the federal workforce.
A live podcast episode featuring conversations with Alex Boris, Dean Ball, and Peter Wildeford exploring AI developments, policy challenges, and forecasts for 2026, covering topics like the RAISE Act, chip sales to China, AI agent capabilities, and potential technological paradigm shifts.
In this podcast episode, David Haber and Zach Perret trace the dramatic rise, fall, and reset of the fintech industry, exploring how the sector went from receiving 25% of venture dollars to nearly zero and is now experiencing a resurgence driven by AI, embedded finance, and new approaches to financial services.
Patrick Ewers, founder of Mindmaven, shares insights on how effective relationship management, strategic delegation, and intentional thinking time can unlock professional potential and create billion-dollar opportunities.
A candid conversation with David George from a16z about AI investment strategies, the changing landscape of venture capital, and why finding founders with exceptional strengths matters more than worrying about theoretical competition.
A comprehensive exploration of America's crime crisis, examining how technology, strategic policing, and innovative public-private partnerships can potentially eliminate crime through intelligent, precise law enforcement approaches.
Ryo Lu discusses how Cursor is transforming software development by enabling designers to become developers, collapsing traditional team boundaries through AI-powered tools that let creators ship code quickly and iterate on their ideas with unprecedented speed.
David George, a General Partner at Andreessen Horowitz, discusses the firm's investment strategy, the evolving landscape of venture capital, the potential of AI startups, and the importance of backing founders with exceptional strengths across various market opportunities.
A deep dive into AI's potential transformative impact, exploring whether it's just another platform shift or something closer to electricity, examining technological bottlenecks, industry implications, and the uncertain path to realizing AI's full potential.
Tristan Harris discusses the existential risks of AI, arguing that unregulated artificial intelligence could lead to the collapse of teen mental health, job displacement, and the concentration of power in the hands of a few tech companies.
A venture capital roundtable featuring Bryan Kim and David Clark explores the AI landscape, discussing startup valuations, growth potential, and whether the current AI market constitutes a bubble, while highlighting innovative strategies for founders and emerging technological opportunities.
A16z partners discuss how AI coding is transforming software development, potentially creating a $3 trillion market by reimagining development workflows, tools, and value creation through AI agents.
Naveen Rao's Unconventional AI is pursuing analog computing systems inspired by brain physics to create more energy-efficient AI hardware that could fundamentally transform computing and potentially bring us closer to understanding intelligence.
A16z General Partner Anish Acharya discusses the resurgence of consumer tech, AI's transformative potential, and key insights for founders navigating the rapidly evolving tech landscape in 2026.
An insider's deep dive into building a durable venture capital firm by focusing on high-access Series A investments, operational support for founders, and maintaining consistent performance across investment vintages.
The podcast discusses how AI moats still matter, with the key difference being that software can now do actual work, transforming market opportunities from IT spend to labor spend, and creating trillion-dollar opportunities in unexpected spaces.
David George shares insights into a16z's growth investing strategy, focusing on AI investments, identifying market leaders, and backing "technical terminator" founders across various technology sectors.
Ben Horowitz shares insights on leadership, culture, and entrepreneurship, revealing his approach to tough conversations, the importance of confidence in CEOs, and his passion for supporting pioneers in industries like hip hop through his Paid in Full Foundation.
Russ Fradin discusses the urgent need for measuring AI productivity in enterprises, revealing that companies are spending $700 billion on AI tools without understanding their actual impact, and his company Larridon is building the measurement infrastructure to help businesses determine whether their AI investments are truly driving productivity.
A deep dive into how OpenAI is shifting from a single general-purpose model to a portfolio of specialized systems, discussing model customization, fine-tuning, agent workflows, and the evolving landscape of AI platforms.
Ben Horowitz discusses how the US has lost ground in AI to China through restrictive policies, emphasizing the importance of open-source AI development and the critical role of cultural values encoded in AI model weights.
Margit Wennmachers, head of marketing for a16z, reveals how she helped Marc Andreessen and Ben Horowitz transform venture capital by breaking unwritten industry rules, weaponizing transparency, and marketing themselves as authentic entrepreneurs with compelling ideas.
Marc Andreessen discusses how AI is democratizing access to cutting-edge technology, transforming business strategy, and reshaping innovation by spreading first to individuals and small businesses before reaching large corporations and government.
Mel Williams, co-founder of TrueBridge Capital, shares insights on the venture capital landscape, discussing the power of signal, the importance of concentrating on top-performing managers, and the exciting potential of AI while navigating a frothy investment environment.
Robinhood CEO Vlad Tenev discusses how the company is democratizing finance by breaking Wall Street rules, tokenizing private company shares, running prediction markets, and building a platform that makes everyone an owner.
Gene Ludwig and Paolo Bertolotti of ModernFi discuss how their innovative deposit network solution could help community banks survive future financial crises by creating a bank-owned consortium that addresses technology, economic, and alignment challenges in the banking ecosystem.
A deep dive into how Silicon Valley is returning to its Cold War roots, rebuilding America's industrial base through defense, energy, aerospace, and manufacturing technologies, driven by a new generation of founders who understand the urgent need to innovate and compete with China.
Jason and Alex discuss the latest AI models from xAI (Grok 4.1) and Google (Gemini 3), examining their performance improvements and potential impact on the tech industry's "doomerism" while also exploring broader concerns about AI's potential job displacement.
Joshua Browder, founder of DoNotPay, discusses his journey from creating iPhone app themes to building a consumer rights technology company, sharing insights about his anti-authority approach, startup challenges, and commitment to helping people fight unfair fees and systems.
Fei-Fei Li and Justin Johnson discuss their journey in AI, founding World Labs to develop spatial intelligence technology that can perceive, generate, and interact with 3D worlds, bridging the gap between virtual and physical realms.
Rocket Mortgage CEO Varun Krishna and a16z's Alex Rampell discuss how housing has become a wealth transfer machine, with the median homebuyer age rising from 30 to 38, and explore strategies to transform the homeownership experience through technology, vertical integration, and AI-driven solutions.
The episode explores how Harvey AI is revolutionizing the legal profession with AI technology and OpenRouter is simplifying AI model access by providing a unified API for developers to easily switch between and experiment with different language models.
An insightful exploration of AI innovation featuring top investors and founders discussing the transformative potential of AI across infrastructure, applications, open collaboration, and emerging opportunities in various sectors.
In this episode, Eugenia Kuyda discusses how personal software will transform from a developer monopoly to a creative medium where anyone can create, remix, and share mini-apps as easily as posting a video, focusing on deep personalization and making AI interfaces more intuitive and accessible.
ElevenLabs' CEO Mati Staniszewski discusses how the company builds AI audio technology at lightning speed through small autonomous teams, global hiring, a Voice Marketplace that has paid creators $10M, and a strategic approach to transitioning from a creator brand to an enterprise platform.
David Sacks discusses the Trump administration's approach to AI and crypto, emphasizing the importance of innovation, regulatory clarity, and maintaining America's technological leadership while preventing overregulation and preserving the decentralized, permissionless nature of technological development.
Marc Andreessen and Ben Horowitz discuss the current state of AI, its potential limitations, and the evolving landscape of technological innovation, exploring topics ranging from machine intelligence and creativity to the geopolitical implications of AI development.
A deep dive into the AI landscape explores whether we're in an AI bubble, examining infrastructure spending, market structure, and the potential transformative impact of AI across technology, business models, and the global economy.
A deep dive into the latest venture capital news, including OpenAI's restructuring, Andreessen Horowitz's $10B fund raise, Mercor's $350M round, and discussions on startup valuations, AI investment strategies, and the challenges facing companies like Amazon and Ramp.
A deep dive into the unprecedented AI infrastructure buildout, exploring how power, compute, and networking are being reinvented across chips, data centers, and global systems, with experts from Google and Cisco discussing the massive scale and geopolitical implications of this technological transformation.
In this episode of the a16z Podcast, Marc Andreessen, Katherine Boyle, and Erik Torenberg discuss how iconic films like "Once Upon a Time in Hollywood," "Tropic Thunder," "Oppenheimer," and "Fight Club" reveal different cultural moments and transformations in American society.
Marc Andreessen and Amjad Masad discuss how AI agents powered by reinforcement learning and verification loops are enabling anyone to build complex software by simply describing it in English, while exploring whether this rapid progress in coding represents a path to true artificial general intelligence or a local maximum trap.
Reducto's co-founder and CEO shares how the startup pivoted from building long-term memory for language models to creating the most accurate PDF and document processing infrastructure, growing to $5M ARR with just founder-led sales while raising $108M and only burning $1M in capital.
Industry Ventures' Jonathan Roosevelt explains how the firm leverages its 650-fund network and $8 billion in AUM to identify co-investment opportunities through rigorous diligence that emphasizes direct customer validation and manager credibility over social proof.
AI is sparking a consumer tech renaissance by enabling new categories like emotional interfaces and companionship products that large tech companies won't build, while democratizing product creation so that individual builders can launch ambitious applications from idea to deployment in days.
Keith Rabois discusses the potential of AI, geopolitics, and economic innovation, exploring topics ranging from sovereign AI and the future of big tech to the Middle East peace process and the importance of asking the right questions.
Ali Horowitz and Ben Ghodsi discuss the founding journey of Databricks, including navigating early challenges, making strategic pivots, building a high-performance culture, and turning down acquisition offers to pursue a bigger vision.
Zach Dell, CEO of Base Power, discusses his mission to lower electricity costs through innovative battery storage technology, vertical integration, and distributed grid solutions to drive energy abundance and accessibility.
A discussion with Columbia CS Professor Vishal Misra about the limitations of Large Language Models (LLMs) and why they cannot discover fundamentally new science or create entirely new paradigms of knowledge.
In this episode, the hosts discuss the future of energy with Zach Dell, CEO of Base Power, and then explore the philosophical influence of Nick Land in Silicon Valley, delving into his complex intellectual journey and impact on technological thinking.
Liam Fedus and Ekin Dogus Cubuk discuss their startup Periodic Labs, which aims to train AI systems to accelerate scientific discovery by using physical experiments as a reinforcement learning signal, with a focus on discovering high-temperature superconductors.
A discussion with Liam Fedus and Ekin Dogus Cubuk about founding Periodic Labs, an AI research company aimed at accelerating scientific discovery by training AI systems to conduct physics and chemistry experiments through real-world feedback and iteration.
A conversation with Marc Andreessen, John Collison, and Charlie Songhurst exploring tech's big questions, including the history of Silicon Valley, AI as a platform shift, the nature of tech bubbles, and the evolving media landscape.
A wide-ranging conversation with Marc Andreessen and Charlie Songhurst exploring Silicon Valley's history, the potential of AI, the future of media, and the transformative impact of new technologies on society and institutions.
Jennifer Edwards shares insights on bridging communication gaps by focusing on self-awareness, psychological flexibility, and genuine human connection through techniques like asking open-ended questions, being present, and understanding that connection starts with who you're being, not just what you're doing.
Periodic Labs, co-founded by ChatGPT creator and former DeepMind physicist, is building an AI physicist to accelerate scientific discovery by combining large language models, simulations, and experimental data to tackle challenges like high-temperature superconductivity.
A wide-ranging podcast episode exploring topics like crypto, American dynamism, parenting, education, internet culture, and the evolving media landscape through conversations with a16z crypto team member Eddie Lazarin.
Jason Carman discusses the creation of his short film "Planet," a sci-fi story about an engineer building an artificial planet, while sharing insights into his company Story's mission to inspire optimism through storytelling and filmmaking.
A deep dive into venture capital research reveals surprising insights, including how most startup failures stem from raising too much money too early, and the importance of origination-stage investing in uncovering truly innovative companies.
OpenAI's Mark Chen and Jakub Pachocki discuss their research journey towards creating an automated researcher, exploring the future of AI reasoning, and the challenges of advancing machine learning capabilities across various scientific domains.
In this episode, Aaron Levie discusses how AI is transforming software development, startup innovation, and productivity across industries, highlighting the massive potential for bottom-up AI adoption and new AI-native companies.
A thoughtful exploration of communications as a uniquely human skill, storytelling techniques, and how founders can build compelling narratives that attract talent and shape perceptions of their companies.
A comprehensive exploration of America's scientific challenges, highlighting NIH's new $50 million autism initiative, potential breakthroughs in drug research, and the critical need to rebuild public trust in science through rigorous, transparent research and humble communication.
A detailed exploration of the US-China tech rivalry, focusing on NVIDIA's chip dispute, the potential TikTok deal, and a nostalgic trend among China's Gen Z reflecting economic challenges and changing social dynamics.
A deep dive into how AI agents could revolutionize online shopping, from product research to price optimization, potentially disrupting traditional e-commerce platforms like Google and Amazon.
A deep dive into the potential of virtual cell models and AI to accelerate scientific discovery, drug development, and biological understanding by creating more predictive and efficient research tools.
Ben Horowitz discusses the challenges of being a CEO, emphasizing the importance of making difficult decisions and not hesitating, even when both choices seem terrible. He shares insights on leadership, startup culture, and the critical role of confidence and managerial leverage, drawing from his experiences as a founder, investor, and author.
Ben Horowitz, co-founder of a16z, shares insights on leadership, startup challenges, and the importance of running towards fear rather than away from it. He emphasizes that success is built through a series of small, difficult decisions and that founders must maintain confidence even when facing seemingly impossible choices.
In this episode of the a16z Podcast, Matt Perrault and Colin McHugh discuss the "Little Tech Agenda" for AI policy, advocating for a regulatory approach that focuses on harmful use rather than development, and ensures startups can compete in the AI landscape while maintaining national technological leadership.
ElevenLabs co-founder Mati Staniszewski discusses the company's rapid growth from a dubbing-focused startup to a leading AI voice technology platform, achieving $200 million in annual recurring revenue in just 15 months. He shares insights on building a global AI company from Europe, the importance of research and product innovation, and the challenges of scaling a technology startup.
In this a16z Podcast episode, Alex, founder of Stainless, discusses the evolution of APIs as the "dendrites of the Internet" and how his experience at Stripe led him to create a platform for generating high-quality SDKs and developer tools. The conversation explores the emerging challenges of designing APIs for both human developers and AI agents, highlighting the importance of thoughtful interface design, type safety, and context management in the era of large language models.
Shaka Senghor shares his transformative journey from incarceration to freedom, discussing how he overcame personal trauma and self-imposed mental prisons through journaling, forgiveness, and resilience. In a powerful conversation with Oprah Winfrey, he explores the true meaning of freedom, emphasizing that liberation begins in the mind and requires ongoing personal work.
Albert Azout of Level Ventures discusses how venture capital firms can generate alpha by understanding market changes, network dynamics, and emerging opportunities, focusing on strategies like criticality investing and leveraging data-driven insights. The conversation explores the complexities of venture investing, including the importance of networks, the challenges of predicting market shifts, and the evolving landscape of technology investment.
A16z podcast hosts Martin Casado and Leo Polovitz explore the nuanced debate around consensus investing in venture capital, discussing whether being non-consensus is overrated or essential for identifying breakthrough companies. They delve into market efficiency, the importance of understanding investor sentiment, and the potential returns from investing in companies that challenge conventional wisdom.
Jack Altman sits down with Martin Casado, a general partner at Andreessen Horowitz, to discuss the shifting dynamics of venture capital, the rise of AI infrastructure, and the importance of media and talent in the tech ecosystem. They delve into the evolution of venture capital, exploring specialization, investment strategies, and the transformative potential of AI across various industries.
Martin Casado discusses his journey at Andreessen Horowitz, the evolution of venture capital, and the importance of specialization in a rapidly growing tech market. He shares insights on AI, infrastructure, open source, and the changing role of venture capitalists in supporting founders and navigating competitive landscapes.
Here's a two-sentence description of the episode: Chris Best, co-founder of Substack, discusses the platform's mission to create a new economic engine for culture by supporting independent writers and media creators. The episode explores Substack's origins, its stance on free speech during challenging times, and its vision for the future of media in an attention-scarce world where technology can either degrade or elevate human culture.